Studies to understand the mechanistic role of acetyl 11 keto and#946; boswellic acid in modulating the chain of molecular events involved in benzo apyrene induced lung carcinogenesis

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dc.contributor.guideDhawan, D.K. and Garg, M.L.
dc.coverage.spatialBiophysics
dc.creator.researcherBhardwaj, Priti
dc.date.accessioned2020-11-11T11:52:13Z
dc.date.available2020-11-11T11:52:13Z
dc.date.awarded
dc.date.completed2020
dc.date.registered2015
dc.description.abstractThe study was conducted to understand the chemopreventive role of Acetyl-11-keto-betaboswellic acid in modulating the molecular events involved in Benzo(a)pyrene induced lung newlinecarcinogenesis in SD female rats. The investigations revealed that Boswellic acid supplementation regulates the activities of biotransformation and antioxidant enzymes that result in reduction of oxidative stress during initiation and promotion of carcinogenesis. Further, Boswellic acid modulates the membrane dynamics including inflammatory pathways which are the hallmarks of lung carcinogenesis and also induces apoptosis. Therefore, the study concludes that Boswellic acid is a potential candidate in affording chemoprevention during conditions that lead to lung carcinogenesis. newline newline
dc.description.noteBibliography 132-177p.
dc.format.accompanyingmaterialCD
dc.format.dimensions-
dc.format.extent177p.
dc.identifier.urihttp://hdl.handle.net/10603/306552
dc.languageEnglish
dc.publisher.institutionDepartment of Biophysics
dc.publisher.placeChandigarh
dc.publisher.universityPanjab University
dc.relation-
dc.rightsuniversity
dc.source.universityUniversity
dc.subject.keywordBoswellic acid
dc.subject.keywordChemoprevention
dc.subject.keywordInflammation
dc.subject.keywordLung cancer
dc.subject.keywordMembrane dynamics
dc.titleStudies to understand the mechanistic role of acetyl 11 keto and#946; boswellic acid in modulating the chain of molecular events involved in benzo apyrene induced lung carcinogenesis
dc.title.alternative
dc.type.degreePh.D.

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