The role of oxidative stress sirtuin 1 level and gene polymorphism in diabetic nephropathy

The role of oxidative stress sirtuin 1 level and gene polymorphism in diabetic nephropathy

dc.contributor.guide	GSR Kedari
dc.coverage.spatial
dc.creator.researcher	Hari Priya S
dc.date.accessioned	2021-11-02T07:27:22Z
dc.date.available	2021-11-02T07:27:22Z
dc.date.awarded	2021
dc.date.completed	2021
dc.date.registered	2015
dc.description.abstract	Traditionally biomarkers are used to monitor and investigate the newlineprogression of diabetic nephropathy. Recent studies showed advanced newlinebiomarkers which are significantly increased in type 2 diabetes mellitus and newlineserve as early biomarkers for glomerular and tubular functions. Apart from newlinethese biomarkers, recently genome-wide associations are discovered and newlinealso several novel genetic variants associated with diabetic nephropathy. newlineElucidating of such genes may be useful for early identification of at-risk newlineindividuals. The present study emphasizes molecular mechanism of sirtuin 1 newlinesnp s rs 3818292 and rs10823108 in diabetic nephropathy. To fill this gap, the study was undertaken to address the impact of genetic events in diabetic nephropathy in south Indian population. newline
dc.description.note
dc.format.accompanyingmaterial	None
dc.format.dimensions
dc.format.extent
dc.identifier.uri	http://hdl.handle.net/10603/346640
dc.language	English
dc.publisher.institution	Department of Biochemistry
dc.publisher.place	Chennai
dc.publisher.university	Saveetha University
dc.relation
dc.rights	university
dc.source.university	University
dc.subject.keyword	Genetics and Heredity
dc.subject.keyword	Life Sciences
dc.subject.keyword	Molecular Biology and Genetics
dc.title	The role of oxidative stress sirtuin 1 level and gene polymorphism in diabetic nephropathy
dc.title.alternative
dc.type.degree	Ph.D.