Analysis of Carotid Stenosis Under Different Plaque Configuration

Abstract

In this work, the hemodynamic parameters of artery are presented to help in newlineunderstanding the vascular diseases which is caused due to the deposition of stenosis. newlineThe software tool Computational Fluid Dynamics (CFD) has been used for studying newlinecomputational techniques which gives pavement in the design of the geometrical newlinemodel of arteries and its simulation analysis. Different parameters like shape, size and newlineposition of stenosis varies from person to person has been studied. The work is further newlineextended to examine the phenomenon of variation of shape, size and position of newlinestenosis by numerical simulation of blood flow in healthy and stenosed artery having newlinedifferent plaque shape and size. newlineBy considering various anatomical conditions the hemodynamic parameters were newlinecalculated for healthy and stenosed artery for understanding the development of newlinestenosis in the carotid artery. The analysis was performed by using commercially newlineavailable software ANSYS CFX (version 16.2, 2015). At the arterial bifurcation the newlineflow velocity reduces which in turn reduces the wall shear stress due to the backflow newlineand oscillatory behavior of flow. The region of low wall shear stress is favorable for newlinethe development of atherosclerosis plaque. Geometry and size of stenosis affects the newlinehemodynamic parameters of artery. The hemodynamic parameters such as WSS, newlinevelocity and pressure for various geometrical model having different shape and size of newlinestenosis were calculated and compared. From this work we can observe that the artery newlinehaving maximum area of blockage is an important factor for the measurement of the newlineseverity level because it causes significant changes in flow velocity which may cause newlinefatal conditions and more prone to rupture. These computation simulations help in newlinediagnosis of patient having atherosclerosis. newline