PAMAM Dendrimers with modified Polyol Core as homogeneous catalysts in organic synthesis

Abstract

newlineDendrimers, the novel class of polymers, having the characteristic newlinefeatures like their spherical shape, nano size, high level of control over the newlinearchitecture, molecular uniformity, surface functionality, branching length and newlinedensity, make various applications in different areas like catalysis, drug newlinedelivery, energy transfer and molecular recognition etc. The field of dendritic newlinecatalysis is one of the most promising potential applications of dendrimers, newlinewhere the molecule itself acts as the catalytic site or as a soluble support for newlinecatalytically active species. newlineThe large size of dendritic catalysts compared to products allows easy newlineremoval from the medium and reuse of the catalyst several times. These newlinecatalysts are active under green reaction conditions and reduce the use of newlineorganic solvents. Thus the green reaction delivery and high efficiency makes newlinedendritic organocatalysis an emerging area of research. Homogeneous catalysis newlineby dendrimers is interesting, because both the catalyst and the reactants are in newlinethe same phase, which offers improved selectivity, high activity, good newlinereproducibility and avoid mass transfer limitations by virtue of intimate contact newlinebetween the catalyst and reactant(s).