Molecular signaling pathways of recombinant human cripto 1

Abstract

Human oncofetal protein Cripto 1 CR 1 is considered as a potential biomarker and target for cancer therapy CR 1 is overexpressed in various types of cancers including colorectal breast nasopharyngeal and gastric cancer It has been shown that Cripto 1 activates several processes linked with neoplasia including cell proliferation The mitogenic effect of CR 1 has been observed in various experimental systems However the finer molecular details of CR 1 mediated mitogenic signaling and the