A Study on the relationship of quality of sleep with serum and salivary melatonin in periodontitis

Abstract

An integral part of good health and quality of life is oral health. Life newlineexpectancy and good quality of life are dependent on systemic health of newlinean individual, which can be adversely affected by poor oral health.In periodontitis, damage to periodontal tissues results from free newlineradicals generated as a consequence of host-bacterial interactions. newlineIncreased generation of free radicals is associated with decreased newlineantioxidant defense mechanisms. This imbalance between the prooxidant newlineand antioxidant systems may further lead to oxidative destruction and a newlinemarked deterioration of periodontal tissue.A recent systematic review emphasized the importance of healthy newlinesleep practices. Sleep loss and sleep disorders have a wide range of newlinedeleterious health consequences including an increased risk of newlinehypertension, diabetes, obesity, depression, heart attack and stroke.Literature search reveals that no clinical studies were done to newlinecompare chronic periodontitis and sleep quality and to correlate them with newlinesalivary and serum melatonin levels. Thus currently, a literature lacuna newlineexists on the assessment of sleep quality before and after non-surgical newlinetherapy and correlating them with salivary and serum melatonin levels. In newlinelieu of the above, this clinical trial aims to assess the additive effect of newlinesleep hygiene instructions and nonsurgical therapy with serum and newlinesalivary melatonin levels in chronic periodontitis patients and compare newlinewith nonsurgical therapy alone. newline