A Versatile Colorimetric Sensing Strategy Based on Functionalized Metal Organic Frameworks as An Effective Detection of Pesticides and Biomolecules

Abstract

In recent years, contamination by pesticides and biomolecules has harmed the environment, food safety, and public health. pesticides and biomolecules, which release toxins into foods, water bodies, industrial effluents and illegal human activity, can enter the food chains of people, freshwater ecosystems and animals from various anthropogenic sources. This causes several adverse effects on the biological systems of humans and animals. Hence, appropriate measures must be taken to detect pesticides and biomolecules in food and water samples. Numerous detection systems have been employed to control pollution. Among them, the colorimetric and nanomaterials-based biosensors are highly sensitive, selective, simple, and cost-effective. Therefore, colorimetric nanozyme-based biosensors (nanomaterials) are the most effective method for detecting pesticides and biomolecules. newlineIn the field of colorimetric biosensors, the peroxidase-like activity and colorimetric signal generation efficiency of MOF-based nanomaterials have attracted much attention. As a result, in this research, we established a multi-functional nanomaterial including S, N-CDsatCe-MOF, NiCu-MOF, BiCu-MOF, and FeCu-MOF NS. Several analytical techniques were used well characterize the synthesized materials. In the sensing mechanism, pollutants are strongly adsorbed onto the nanomaterial surface through several non-covalent interactions, including complex formation and and#960; and#960; interactions, resulting in a decrease in colorimetric absorbance and an increase in intensity. Thus, the S, N-CDsatCe-MOF nanozyme were utilized in a new biosensor for Hg2+ ions and thiophanate methyl based on the colorimetric peroxidase nanozyme technique. The suggested detection method resulted in a good dynamic range of 0 to 15 and#61549;M and 0 to 14 and#61549;M and a low LOD of 0.01 and#61549;M and 0.03 and#61549;M for Hg2+ ions and thiophanate methyl, respectively newline