Significance of the Canonical Wnt and#946; Catenin Signaling Pathway in Breast Cancer

dc.contributor.guide	Gayatri Rath, Ranju Ralhan and Dinesh Bhatnagar
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dc.creator.researcher	Chandra Prakash Prasad
dc.date.accessioned	2017-01-25T10:41:38Z
dc.date.available	2017-01-25T10:41:38Z
dc.date.awarded	01/12/2011
dc.date.completed	12/2009
dc.date.registered	2006
dc.description.abstract	In conclusion, our data suggests the activation of Wnt/and#946;-catenin signaling in invasive ductal breast carcinomas and one of the plausible mechanisms responsible for this aberrant activation is the epigenetic silencing of key Wnt signaling molecules (like APC and E-cadherin). Our results also highlight the effect of curcumin on Wnt/and#946;-catenin signaling components in breast cancer cells. The inhibition of cell proliferation and induction of apoptosis in breast cancer cells with curcumin administration provide evidence for its potential for cancer treatment.
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dc.format.accompanyingmaterial	CD
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dc.identifier.uri	http://hdl.handle.net/10603/127628
dc.language	English
dc.publisher.institution	University School of Medicine and Para Medical Health Sciences
dc.publisher.place	Delhi
dc.publisher.university	Guru Gobind Singh Indraprastha University
dc.relation
dc.rights	university
dc.source.university	University
dc.title	Significance of the Canonical Wnt and#946; Catenin Signaling Pathway in Breast Cancer
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dc.type.degree	Ph.D.