Evaluating Urinary N Telopeptide As A Diagnostic Test For Osteoporosis

Abstract

Abstract newlineOsteoporosis is a silent disease until it is complicated by trivial fall fractures There is an increasing interest within the orthopedic community in the noninvasive cost effective measurement of the bone mineral density The aim of the study is to assess whether urinary N telopeptide level can be a new diagnostic tool in diagnosing osteoporosis and Material This prospective study was done at Sri Ramachandra Medical Centre SRMC hospital from October 2015 to October 2017 The study was conducted among patients who comes to SRMC as inpatient or outpatient with suspected osteoporosis and underwent dual energy Xray absorptiometry DXA scan and urinary N telopeptide The inclusion criteria were women aged 65 or older women aged less than 65 with risk factors younger postmenopausal women with one or more risk factors men aged 70 or older men less than 70 with risk factors and any above group patients who comes within 24 hours following trivial fall fractures The exclusion criteria were pathological fracture history of any illness affecting bone metabolism The results from DXA scan were taken as gold standard against urinary Ntelopeptide Then the patients were divided into two groups control and study The control group contains patients who had normal DXA while study group contains patients having either osteopenia or osteoporosis Based on our inclusion and exclusion criteria 110 persons were included in the study We had 60 study and 50 controls patients We had 88 females and 22 males The results obtained were statistically analyzed In our study we had 18 point 2 percent osteopenic and 36 point 4 percent osteoporotic patients The mean value of urinary N telopeptide in control was 49 point 8 and in case was 182 point 5 The standard deviation of urinary Ntelopeptide value in case was 159 point 9 Conclusion Urinary Ntelopeptide can give reproducible results and be able to assist in the evaluation of the quantity as well as the quality and be a good judge of some ones risk of fracture Hence urinary Ntelopeptide can b