Formulation and Evaluation of Temozolamide and Ketoconazole loaded Folate grafted Solid Lipid Nanoparticles for Brain Tumors

Abstract

Brain is one of the largest and most complex organs in the human body. newlineIt is made up of more than 100 billion nerves that communicate in trillions of connections called synapses. Brain and spinal cord together form the central nervous system (CNS)(Ferlay J etal, 2010). CNS is the core of our existence. It controls our personality, thoughts, newlinememory, intelligence, speech and understanding, emotions, senses, and basic body functions,as well as how we function in our environment Human brain is hugely interconnected but three major components can be identified: the cerebrum, the cerebellum and the brain stem. newline