An Open Label Comparative Clinical Study to Assess the Effect of Dasamoola Ksheeradhara as an Add On Therapy With Standard Care in Conventional Medicine in Diabetic Peripheral Neuropathy

Abstract

Diabetic Peripheral Neuropathy (DPN) is the key initiating factor for the newlinedevelopment of diabetic foot ulcers and the most common cause of lower limb amputation. newlineClinical or subclinical neuropathy has been identified in nearly two-thirds of diabetic newlinepatients. All patients with DM can develop neuropathy, with its prevalence increasing with newlinethe duration of DM. Diabetic neuropathy is defined as The presence of symptoms newlineand/or signs of peripheral nerve dysfunction in people with diabetes after exclusion of newlineother causes. newlineDiabetic Peripheral Neuropathy is predominantly sensory neuropathy or sensory newlinemotor neuropathy. Glycemic control and duration of diabetes are regarded as the main newlinereasons of DPN along with other factors like raised triglyceride levels, hypertension, newlineobesity, and smoking. newlineIn Ayurveda, symptoms of DPN can be seen in poorvarupa and upadrava of Prameha newlineespecially Madhumeha. It can be further compared to that of Raktavrutha Vata, a condition newlinewhen Vata gets Avruta by Rakta, all the symptoms of DPN is seen. There are symptoms newlinelike excessive pain associated with a burning sensation in the area between Tvak and Mamsa, newlineand also svayathu,raga, and formation of mandalas. Charaka has mentioned the treatment newlinefor Raktavruthavata treatment should be in similar lines with that of Vatarakta. So along newlinewith the treatment of Madhumeha, Vatarakta treatment also holds a vital part in treating newlineDiabetic Peripheral Neuropathy. newlineKand#7779;heera Dhand#257;ra (irrigation with milk) has benefits on the nervous system and Vand#257;ta- newlinePitta disorders. Among the four types of Sveda told by Vand#257;gbhaand#7789;a, the Drava variety is newlineindicated for vitiated Pitta and Rakta. The Koand#7779;and#7751;a Pariand#7779;eka (lukewarm irrigation) of newlineDasamoola Ksheera (milk boiled with Dasamoola) over the entire body is indicated in newlineVand#257;tarakta Cikitsa (treatment of gouty arthritis) with the predominance of Vand#257;ta to relieve newlinepain. newline