Synthesis characterization and chelating properties of novel oligomeric Azo dye

Abstract

newline The produced research work comprises the aspect of polymeric azo dyes with pendent 8-hydroxy quinoline ligands. newlineChelating agents are becoming of increasing importance in analytical chemistry such as in gravimetric, titrimetric and colorimetric measurements. New types of chelates and chelating agents are constantly under investigation, for possible analytical and industrial applications. The ever increasing number of publications on this subject may realize the growing importance of the use of metal chelates in analytical chemistry. newline newline It was G.T. Morgan and Drew who first coined the name CHELATE from the Greek word CHELE used for crabs claw to designate the cyclic structures which arise from the union of metallic ions with organic or inorganic molecules, with two or more points of attachments to produce a close ring. To form metal chelates of an organic compound, an organic compound must have two or more atoms usually oxygen or nitrogen, capable of coordination with a metal ions, i.e. it must be a base having a pair of unshared electrons available for coordination. These coordinating atoms are so arranged that rings of five or six member including the metal ion will be formed newline 8-Hydroxyquinoline (8-quinolinol, oxine) might be thought to function as a phenol, but of the 7 isomeric hydroxyquinolines only oxine exhibits significant antimicrobial activity, and is the only one to have the capacity to chelate metals. If the hydroxyl group is blocked so that the com-pound is unable to chelate, as in the methyl ether, the antimicrobial activity is destroyed. The relationship between chelation and activity of oxine has been in¬vestigated. newline Certain halogen derivatives of 8-hydroxyquinoline have a record of thera¬peutic efficacy in the treatment of cutaneous fungus infections and also of amebic dysentery.