Screening of Physicochemical Pharmacological Microbiological Properties and Possible Pharmaceutical Applications of Some Selected Plant Constituents

Abstract

The present study Screening of physicochemical, pharmacological, microbiological properties and possible pharmaceutical applications of some selected plant constituents , may be concluded as the application of separated plant components i.e. resin from Ipomoea quamoclit and mucilage from Aegle marmelos can be used as a good pharmaceutical excipient, especially as a binding agent in the formulation of granules and tablets. As a disintegrating agent, for tablets and granules, newlinethe separated mucilage performs better than the resin and is comparable to the existing standard disintegrants used (sodium starch glycolate, cross carmellose and potato starch) in the study. As an agent for sustaining the drug release, separated resin was found to be better than the mucilage, as it did not perform well in sustaining the release but, only more or less equivalent to the standard polymer (HPMC) used in the study for comparison. The selected natural resin and mucilage are low cost alternatives to their synthetic counterparts which may be due to their versatile properties, newlinebiocompatible nature, physicochemical and microbiological stability. Hence, the selected resin and mucilage can be used as natural excipients for development of different dosage forms. newline newline