Genomic variation in production linked candidate gene and its association with performance and egg quality traits and kinetics of antibody response to vaccines in uttara and kadaknath native chickens

Abstract

The present study was conducted to evaluate the growth, egg production, egg quality traits and kinetics of antibody newlineresponse to NDV and IBDV vaccines of Uttara and Kadaknath chicken, their genotyping with respect to egg production newlineassociated gene ie. MTNRIC, to associate candidate gene polymorphism with production traits and to associate level of newlineexpression of candidate with egg production trait in Uttara and Kadaknath chicken. The data on body weights from day old to newline40 weeks at four weeks interval, ASM, BW20, BW 32, BW40, EW32, BW40, EW40, EP32 and EP40 were recorded on 300 newlinefrom two hatches pedigreed birds maintained at IPF, Nagla, G.B. Pant University of Agriculture and Technology, Pantnagar, newlineUttarakhand. Data were analysed by LS ANOVA using mixed model, wherein sire was taken as random effect and hatch as newlinefixed effect. The estimated least square means of CW, BW4, BW8,BW12,BW16 and BW20 were 36.99±0.14, 175.43±0.19, newline460.46±0.18, 806.58±0.28, 1139.05±0.72 and 1334.31±6.70 g respectively.Sire had significant effect (Pand#8804;0.05) on CW, BW12 newlineand highly significant effect (Pand#8804;0.01) on BW20. Hatch had significant effect (Pand#8804;0.05) on CW. Effect of sex of the bird was newlinefound be highly significant (Pand#8804;0.01) from CW up to 20-week.Heritability estimates were 0.18±0.14, 0.42±0.11, 0.01±0.10, newline0.12±0.13, 0.05±0.11 and 0.68±0.25 respectively. Genetic correlation of BWwere ranged from -0.96±1.01 to 0.57±0.63 and newlinephenotypic correlations were ranged from 0.16 to 0.96.In Uttara birds, the least squares means (LS-means) of ASM, BW20, newlineBW32, BW40, EW32, EW40, EP32 and EP40 were 172.45 ± 0.30 days, 1313.73 ± 0.55, 1570.74 ± 0.57, 1588.77 ± 0.62, newline50.95 ± 0.19, 54.89 ± 0.11, 52.06 ± 0.22 and 74.23 ± 0.19 g respectively. Sire had significant effect (Pand#8804;0.05) on ASM, BW32 newline(Pand#8804;0.01) and BW40 (Pand#8804;0.01). Hatch had significant effect (Pand#8804;0.01) on BW32, BW40 and EP40 (Pand#8804;0.05). Heritability newlineestimates were 0.26 ± 0.21, 0.13 ± 0.18, 0.52 ± 0.27, 0.45 ± 0.25, Not Estimate, 0.18 ± 0.19, 0.12 ± 0.18 and 0.08 ± 0.17 newlinerespectively. BW20, BW-40, ASM, EW40 showed