Development of a tool for pathogen detection using Integrated Multi Omics Approch

Abstract

newlineInfections are caused by harmful microorganisms called pathogens such as bacteria, newlinefungi, or virus. Clinical diagnostics play an important role in infectious disease newlinemanagement and there are various diagnostic methods to identify these pathogens. newlineTraditional culture-based methods are limited, labour intensive and has low data newlinethroughput while molecular based methods such as PCR requires prior knowledge of newlinepathogens and are target specific. These limitations can result in delayed diagnosis, and newlinein some cases the infections are undiagnosable as well. Next-Generation Sequencing newline(NGS) is a high throughput sequencing technology and has recently gained popularity in newlinethe field of clinical microbiology.