Design and synthesis of indoleamine 2 3 dioxygenase 1 inhibitors

Abstract

The contents of this thesis entitled 339 Design and Synthesis of Indoleamine 2 3 Dioxygenase 1 Inhibitors have been divided into four chapters based on the results of experimental work carried out during the research period The introductory chapter Chapter 1 of the thesis describes the various physiological function of the heme protein indoleamine 2 3 dioxygenase 1 IDO1 This chapter also describes the importance of IDO1 as a key therapeutic target for the treatment of diseases like canc