Extraction isolation and characterization of stevia rebaudiana bertoni leaves and evaluating its anti inflammatory activity against ulcerative colitis and adjuvant arthritis in rodent models

Abstract

newline Sucrose is the most common sweetener. Sugar causes obesity, type 2 diabetes, and newlinemetabolic syndrome. Diet-conscious customers are demanding a natural, high-intensity, newlinelow-calorie, non-nutritive, stable sweetener to replace sugar (sucrose) in food and newlinenutraceuticals. Steviol-glycosides are 250-300 times sweeter than sucrose at 0.4% (w/v). newlineAlthough there is much literature on stevioside extraction, these approaches have newlinedisadvantages such as non-green solvents, long extraction durations, and several newlinepurification stages resulting in low yields. Processes create dangerous wastes and newlinebyproducts. Stevioside is anti-diabetic, anti-cancer, anti-ulcer, antiviral, and diuretic newline