Total Synthesis of Biologically Active Natural Products Involving Asymmetric Induction Using Chiral Catalysis

dc.contributor.guide	Pandey, Satyendra Kumar
dc.coverage.spatial
dc.creator.researcher	Suraksha
dc.date.accessioned	2021-05-18T06:16:08Z
dc.date.available	2021-05-18T06:16:08Z
dc.date.awarded
dc.date.completed	2017
dc.date.registered
dc.description.abstract	We have described herein enantioselective approaches for the synthesis of (+)-serinolamide A, (-)-haliclamide, (+)-petromyroxol, (+)-phomonol, (+)-epi-muricatacin and (-)-6-acetoxy-hexadecanolide employed Trost s DYKAT, MacMillan organocatalyzed aldol reaction, Sharpless AD and Jacobsen s HKR reactions as key steps.. The merits of these synthetic approaches are high enantio- and diastereoselectivity with high yielding reaction steps. All the new compounds were characterized by 1H-NMR, 13C NMR, HRMS, %ee by chiral HPLC and [and#945;]D25 for all new chiral compounds. newline
dc.description.note
dc.format.accompanyingmaterial	None
dc.format.dimensions
dc.format.extent	142p.
dc.identifier.uri	http://hdl.handle.net/10603/326750
dc.language	English
dc.publisher.institution	School of Chemistry and Biochemistry
dc.publisher.place	Patiala
dc.publisher.university	Thapar Institute of Engineering and Technology
dc.relation
dc.rights	university
dc.source.university	University
dc.subject.keyword	Haliclamide
dc.subject.keyword	Petromyroxol
dc.subject.keyword	Serinolamide A
dc.title	Total Synthesis of Biologically Active Natural Products Involving Asymmetric Induction Using Chiral Catalysis
dc.title.alternative
dc.type.degree	Ph.D.