Preparation and evaluation of anticancer drug loaded acronycine nanoparticulate formulation

Preparation and evaluation of anticancer drug loaded acronycine nanoparticulate formulation

dc.contributor.guide	Sharma, Sanjeev
dc.coverage.spatial
dc.creator.researcher	Khatkar, Pooja
dc.date.accessioned	2024-05-27T10:41:57Z
dc.date.available	2024-05-27T10:41:57Z
dc.date.awarded	2023
dc.date.completed	2023
dc.date.registered	2020
dc.description.abstract	The first line of defence against many cancer types is chemotherapy, which is frequently associated with serious side effects. Plant extracts may have anticancer properties. Ursolic acid is one of many signalling pathways in the cancer cell that can be modified by triterpenoids; however they are hydrophobic and have a low bioavailability. Tamoxifen slows the growth of cancer cells by selectively blocking oestrogen receptors, however it carries a substantial and even fatal risk of blood clots, stroke, subsequent endometrial cancer, and thromboembolic events. Drug-loaded nanoparticulate formulations are the answer to the aforementioned issue. The most effective material for encasing a range of medications has frequently been suggested as a combination of polymers and lipids. In the present work, two different nanoformulations were prepared namely, Acronine loaded Eudragit-E nanoparticles (AENPs), Acronine co-delivered Tamoxifen Chitosan gum nanoparticles (ATCNPs). newline
dc.description.note
dc.format.accompanyingmaterial	None
dc.format.dimensions	28
dc.format.extent	xiv, 139 p.
dc.identifier.uri	http://hdl.handle.net/10603/566805
dc.language	English
dc.publisher.institution	Chemistry
dc.publisher.place	Hisar
dc.publisher.university	OM Sterling Global University
dc.relation
dc.rights	university
dc.source.university	University
dc.subject.keyword	Chemistry
dc.subject.keyword	Chemistry Applied
dc.subject.keyword	Physical Sciences
dc.title	Preparation and evaluation of anticancer drug loaded acronycine nanoparticulate formulation
dc.title.alternative
dc.type.degree	Ph.D.