Metabolic Alterations in Preeclampsia
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Abstract
Hypertensive disorders of pregnancy are quite common and form a one of the
newlinecomponent of triad along with hemorrhage and infection. They comprise of a
newlinespectrum of disorders typically classified into categories and stratified according to
newlineseverity. Out of all these, preeclampsia is the most serious (1). Pregnancy is a
newlinephysiological condition in which many changes occur in the interior milieu of the
newlinebody and more emphasis is being given on the metabolic and biochemical
newlinechanges which occur in the blood during normal pregnancy and becomes
newlineexaggerated in complication of pregnancy like preeclampsia (2),(3).
newlinePreeclampsia is one of the most common complications of pregnancy which
newlineis potentially devastating condition that can threaten the life of both mother and her
newlineunborn child. It contributes to one of the top five causes of maternal and fetal
newlinemorbidity and mortality (1),(4). Reports from World Health organization (WHO) in
newline2000 showed the worldwide pooled incidence of preeclampsia for developing
newlinecountries was estimated to be 3.4% and prevalence 9% (5),(4).
newline