Characterization of drug resistant HIV1 mutants of Agra region India by genomic and proteomic approaches

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dc.contributor.guideMohanty, Keshar Kunja and Jena, Srikanta
dc.coverage.spatial
dc.creator.researcherBarik, Sushanta Kumar
dc.date.accessioned2022-04-11T09:00:09Z
dc.date.available2022-04-11T09:00:09Z
dc.date.awarded2021
dc.date.completed2021
dc.date.registered2014
dc.description.abstractA cohort study was focused on the first line ART patients who were recruited at the ART newlinecentre, Sarojini Naidu Medical College, Agra, India from December 2009 to November 2016. newlineA total of 211 patients were selected based on CD4 counts and first line ART in 1-2 Years, gt3- newline4 years, gt5-6 years and had a viral load and#8805;1000 RNA copies/ml were included in this period for newlinegenotypic assay. The genotypic assay was performed following WHO dried blood spot protocol newline2010 and the drug resistance mutations were analysed by Stanford HIV drug resistance data newlinebase, USA. The NRTI and NNRTI drug resistance mutations were observed in the reverse newlinetranscriptase gene. No protease gene associated mutations was observed among the HIV-1 newlineSubtype C infected first line antiretroviral therapy failure patients. newline
dc.description.note
dc.format.accompanyingmaterialDVD
dc.format.dimensionsA4
dc.format.extentAll Pages
dc.identifier.urihttp://hdl.handle.net/10603/373294
dc.languageEnglish
dc.publisher.institutionDepartment of Biotechnology
dc.publisher.placeCuttack
dc.publisher.universityRavenshaw University
dc.relation
dc.rightsuniversity
dc.source.universityUniversity
dc.subject.keywordantiretroviral
dc.subject.keywordBiotechnology and Applied Microbiology
dc.subject.keywordLife Sciences
dc.subject.keywordMicrobiology
dc.subject.keywordpatients
dc.titleCharacterization of drug resistant HIV1 mutants of Agra region India by genomic and proteomic approaches
dc.title.alternative
dc.type.degreePh.D.

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