Comparative Evaluation Of Intra socket Dispersible Piroxicam Tablet And Oral Piroxicam In Postoperative Pain Management After Mandibular Molar Transalveolar Extractions

Abstract

ABSTRACT newlineBACKGROUND newlineSurgical extraction or a transalveolar extraction is a routinely performed oral newlinesurgical procedure in which acute postoperative pain is a commonly newlineexperienced symptom by the patient. The underlying severity of this pain can newlinebe quite variable depending upon the type of surgical procedure. Management newlineof pain after surgical tooth extractions has been a challenging part of dentistry. newlineFor years researchers have sought the best analgesia after tooth extractions. newlineTwo pharmacologic classes of drugs are used in the treatment of pain: the newlinecentrally acting narcotic analgesics, such as codeine and oxycodone, and the newlineperipherally acting analgesics, such as the nonsteroidal anti-inflammatory newlinedrugs (NSAIDs). The choice of drug to be used as an analgesic is based on the newlineduration of analgesic effect and minimal side effects. The NSAlDs are quite newlineeffective against mild to moderate pain; however, not entirely free from adverse newlineeffects. Gastrointestinal alterations like nausea, vomiting, ulcers are commonly newlineassociated with all NSAIDs.Piroxicam is a nonsteroidal anti-inflammatory drug newlineof the oxicam derivatives class used commonly to relieve the symptoms of newlinepostoperative dental pain. newlineIn this study we aim to use a dispersible piroxicam tablet locally(intra-socket) in newlinecomparison with oral piroxicam to evaluate postoperative pain and swelling. newline9 of 99 newlineAIM newlineTo compare the efficacy of intra-socket delivery of piroxicam with oral newlinepiroxicam in postoperative pain management after surgical extraction of newlinemandibular molars. newlineMATERIALS AND METHODS newlineHundred patients who had undergone transalveolar/ surgical extraction of newlinemandibular molars were randomly divided into two groups: group A (oral newlinepiroxicam 20mg), group B (intra-socket piroxicam 20mg). The dispersible newlinepiroxicam tablet was applied to the extraction sockets and covered with newlineresorbable gelatin sponges. Pain after extraction was evaluated using a visual newlineanalog scale (VAS) at 6th and 24th hours postoperatively.