The drug binding pathways and conformational deviations of g quadruplex dna under different chemical and thermal conditions a computational study

Abstract

Nucleic acid sequences containing series of guanine can form G quadruplex structures which are of special interest because of their high thermal stability resistance to denaturing conditions and stiffness Moreover due to the diverse and polymeric nature it draws the attention of the scientific world in significant and diverse fields Chapter 1 introduces the formation and stability of the G quadruplex DNA in different chemical and thermal conditions along with its applications through l...