Understanding pyrimidine and aspartate metabolism in the growth and infectivity of leishmania donovani

dc.contributor.guide	Dubey, Vikash Kumar
dc.coverage.spatial	Biosciences and Bioengineering
dc.creator.researcher	Tiwari, Kartikeya
dc.date.accessioned	2023-04-25T11:30:00Z
dc.date.available	2023-04-25T11:30:00Z
dc.date.awarded	2017
dc.date.completed	2017
dc.date.registered	2011
dc.description.abstract	Dihydroorotase the third enzyme of the de novo pyrimidine biosynthesis pathway of Leishmania donovani was cloned expressed and biochemically characterized in both directions of enzymatic reactions The data revealed a preference for biologically significant forward direction The forward direction enzymatic reaction shows acidic pH optimum in contrast to slightly alkaline pH optimum of reverse reaction Further the enzyme shows both tetrameric and dimeric structures in equilibrium Biotin su
dc.description.note	Not Available
dc.format.accompanyingmaterial	None
dc.format.dimensions	Not Available
dc.format.extent	Not Available
dc.identifier.uri	http://hdl.handle.net/10603/479302
dc.language	English
dc.publisher.institution	DEPARTMENT OF BIOSCIENCES AND BIOENGINEERING
dc.publisher.place	Guwahati
dc.publisher.university	Indian Institute of Technology Guwahati
dc.relation	Not Available
dc.rights	self
dc.source.university	University
dc.subject.keyword	Biotechnology and Applied Microbiology
dc.subject.keyword	Life Sciences
dc.subject.keyword	Microbiology
dc.title	Understanding pyrimidine and aspartate metabolism in the growth and infectivity of leishmania donovani
dc.title.alternative	Not available
dc.type.degree	Ph.D.