Expression of MicroRNA 21 and MicroRNA 375 in Oral Squamous Cell Carcinoma

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dc.contributor.guideMalathi N
dc.coverage.spatialOral cancer
dc.creator.researcherSangeetha N
dc.date.accessioned2020-09-30T05:39:53Z
dc.date.available2020-09-30T05:39:53Z
dc.date.awarded28/08/2020
dc.date.completed28/08/2020
dc.date.registered01/07/2011
dc.description.abstractOral cancer is the third most common cancer of the Indian subcontinent The survival rate of this cancer is in India is less than 30 percent Various factors like tobacco and pan chewing leads to the causation of oral cancer Early diagnostic marker for oral cancer is yet to be discovered MicroRNAs are Gene regulators that control various physiological and pathological pathways in humans The study aimed at analyzing the expression of microRNA 21 and 375 in oral cancer and also analyzed its association clinicopathological parameters of oral cancer patients 25 cases of oral cancer tissues were studied using qRTPCR The expression of microRNA 21 was significantly higher and microRNA 375 was significantly lower in oral cancer tissues compared to the controls There was significant association between smoking and microRNA 21 expression newline
dc.description.noteIntroduction p.1- 14 Review of Literature p.15-36 Methodology p. 37-44 Results p. 45-100 Discussion p.101-111 Summary p.112-113
dc.format.accompanyingmaterialNone
dc.format.dimensions15cms
dc.format.extent1-113
dc.identifier.urihttp://hdl.handle.net/10603/301439
dc.languageEnglish
dc.publisher.institutionDental College
dc.publisher.placeChennai
dc.publisher.universitySri Ramachandra Institute of Higher Education and Research
dc.relation
dc.rightsself
dc.source.universityUniversity
dc.subject.keywordClinical Medicine
dc.subject.keywordClinical Pre Clinical and Health
dc.subject.keywordDentistry Oral Surgery and Medicine
dc.titleExpression of MicroRNA 21 and MicroRNA 375 in Oral Squamous Cell Carcinoma
dc.title.alternative
dc.type.degreePh.D.

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