Familial whole Exome Sequencing to Identify Genetic Variants Associated with Polycystic Ovarian Syndrome in Indians

Abstract

Polycystic Ovary Syndrome (PCOS) is an endocrinological gynecology disorder with heterogeneous representation of the clinical symptoms among its patients. Due to this dynamic nature there is a lack of consensus in the medical community for the diagnosis and treatment. The pathophysiology not being clearly understood adds on to the discrepancies. Genetics has been reported to be a major etiology of PCOS, which is a complex disorder following a non-mendelian pattern of inheritance newline