Attaining protein thermostability a rationalized approach

Abstract

In proteins natural mutation occurs such that it tries to maintain maximum stability while retaining functionality indicating that nature may be rationalizing the way of attaining such mutations Thermophilic proteins are examples of natural mutations that lead to stability of proteins at extreme of temperatures Chapter I of the dissertation work unravels that the mechanism of thermostability has been attributed to the cumulative effect of numerous factors However a guided approach to attain t