Comparative study on the efficacy of auditory brainstem response ABR distortion product otoacoustic emission DPOAE and auditory steady state response ASSR in neonatal hearing screening in Indian population

Abstract

Background newlineEarly diagnosis and immediate intervention play important role in the newlinedevelopment and prognosis of children with hearing loss and decrease the newlineimpact of the condition on the child s social, emotional, intellectual and newlinelinguistic development. Better form of screening will give exact level of newlinehearing loss and pathology that will help for early diagnosis and better newlinetreatment. This study helped to know better form of neonatal screening which newlinecan help to early diagnosis and early interventions. newlineObjectives newlineThe primary objective was to evaluate the efficacy of Auditory newlineBrainstem Response (ABR), Distortion Product Otoacoustic Emission newline(DPOAE) and Auditory Steady State Response (ASSR), in screening the newlinehearing loss in Indian population. The Secondary objective was to find out newlinewhich of the above test is more specific and sensitive in screening the hearing newlineloss in Indian population. The other objective was to find out the association newlinetype of delivery, low birth weight, APGAR score, Family history of hearing newlineloss, age of the mother, gestational hypertension, gestational diabetes and newlinepreterm babies with hearing loss detected through ABR. newlineMethodology newlineStudy design was cross sectional criterion based validity study. 1000 newlineneonates referred from department of neonatology, Sankar Institute of Medical newlineSciences and Research Center, Kerala. After fulfilling the inclusion criteria, newlineNeonates undergone a regular otoscopic examination followed by a newlinetympanometry. Then Neonates were administered all the three diagnostic newlinescreening tests (OAE, ASSR and ABR). The sequence of the tests one after other newlinewas allotted based on block randomization. A 2x2 contingency table cross newlinetabulation method was used to analysis the sensitivity and specificity of tests. newlineFrom the table True positive sensitivity, True negative specificity, false newlinepositive, false negative were analysed. McNemar test was used, newline