Effect of Gamma Sterilization on Gymnema Sylvestre Leaf Extract Infused Polycaprolactone Nanofiber for Effective Wound Dressing Applications

Abstract

Millions of the peoples affected by skin injuries by accidents, burns and surgeries. The current global challenge is microbes becomes resistance against antibiotics. Which causes serious effects in public health. The electrospun nano-fibrous mats has various biomedical applications in regenerative medicines and tissue engineering field. The biomedical applications of the nanofibers due to its characteristics like high surface to volume ratio, mechanical strength, porosity and sustained drug release. newlineWound healing is a complex process, and it can be enhanced by efficient wound dressing. The plant-based medicine has been used for treating various kind of ailments. In Ayurvedic medicine Gymnema sylvestre is used for the treatment of diabetes, inflammation, wound healing, microbial infection, etc. one of the vital phyto-constituents present in the plant is called Gymnemic acid (gymnemagenin) newline