Breast cancer growth and progression role of copper estrogen and nitric oxide

Abstract

Cancer is the leading cause of death worldwide. As per International newlineAgency for Research on Cancer (IARC) 14.1 million new cancer cases newlineoccurred in 2012. Breast cancer was by far the most common cancer newlinediagnosed in women (Ferlay et al, 2010) newlineThe aim of the present study is to evaluate the risk factors for breast newlinecancer and to study the role of copper, estrogen and nitric oxide in the growth newlineand progression of breast cancer in pre and postmenopausal women. newline2.2 Objectives of the study newline1. To evaluate the risk factors for breast cancer in a selected population. newline2. To estimate the levels of copper, estrogen and nitric oxide in different newlinestages of breast cancer in pre and postmenopausal women. newline3. To associate the role of copper, estrogen and nitric oxide in growth newlineand progression of breast cancer in different stages. newlineThis study has shown that breast cancer is caused due to certain risk newlinefactors prevalent in the community and that it occurs at an earlier age than newlineWest. It also explains the role of hormones and copper in the causation of newlinebreast cancer which can be considered to be same as that of the population newlinein general as patients visiting this hospital belong nearly to the same newlinegeographical region of the country. newline