Experimental Investigation of Physicochemical Synthesis and Biochemical Properties of Schiff Based Complex Compounds

Abstract

Chemistry of macrocyclic ligands and their complexes has fascinated scientists across the globe over the past several decades. It is not only the structural novelty of these compounds that keeps chemists interested, but also their many applications in the fields of medicine, biochemistry, bioinorganics, environmental science, industrial science, and photochemical, photophysical and photoelectronics. Because of their connection to biomimetic and catalytic systems, as well as their usage as chelating agents in biology and medicine, aza-macrocyclic compounds have garnered a lot of interest in recent years. They are used in contemporary clinical methods such as magnetic resonance imaging, imaging using radioisotopes, and radiotherapy. It is suggested that a Schiff base ligand has been formed by the emergence of a new strong intensity band at 1640 cm-1, characteristic of (C=N), and the disappearance of bands characteristic of the C=O and -NH2 groups of 2-methyl acetoacetanilide and 1,8-diaminonaphthalene moieties, respectively, in the IR spectrum. All of the complexes show a negative shift in (C=N) of around 15-20 cm-1, indicating that imine nitrogen is involved in coordination to metal ions. There are bands that correlate to the vibrations of the M-N and Phenyl rings at their predicted locations. These complexes include chloro groups as indicated by the development of a new band, which has the shape of an MCL ring around it. There is a conspicuous singlet at 2.35 and 2.11 ppm in the 1H NMR spectra of both the macrocyclic ligand and Zn(II) complex (-CH3; 12H). We see the anticipated locations of protons in the Phenyl Ring. It is possible that secondary amino protons are responsible for the 8.04 ppm signal (C-NH-C; 2H). When compared to ligand, however, Zn(II) complex resonance signals exhibit downfield shifting, which indicates that Zn(II) ion and ligand are coordinated. The non-ionic character of these compounds is shown by molar conductivity measurements. It is clear from the magnetic moments and absorption bands in