Modification of carbon based electrodes as robust scaffolds for electrochemical sensing of vitamins and hormones

Abstract

Electrochemical sensors are for vitamins and hormones are constructed on employing various newlinemodifications (molecular imprinting technology, coating of 2D sheet like materials and also modifying using supramolecular complexing material) on the transducer host, carbon fiber paper electrode (CFP). From our observation, the electrochemical oxidation/reduction current newlineof the analytes studied, intensified significantly on the surface modifications employed over the CFP substrate. Surface morphology was characterized using Field Emission Scanning Electron Microscopy (FESEM), Electron Diffraction X-ray (EDX), X-Ray Photoelectron spectroscopy (XPS), Optical Profilometry and Fourier Transform Infrared Spectroscopy (FTIR). Nyquist plots revealed the least charge transfer resistance at the finally modified working electrodes compared to other control electrodes. Optimization of experimental conditions such as effect of pH, investigating the reaction mechanism via effect of scan rate, number of cycles for the electrodeposition of the film in order to achieve maximum current response and potential window were studied in detail by using cyclic voltammetry (CV). Quantification of the analytes was performed using Differential Pulse Voltammetry (DPV). newlineAnalytical corroboration for real samples were carried out using the finally modified newlineelectrode. Therefore, all the works carried out have established simplicity and selectivity in the principle of the novel approach in the development of an ultrasensitive voltammetric sensor for vitamins and hormones studied.