Phytochemicals mediated synthesis And functionalization of iron oxide Cuo zno nanoparticles and hitosan Films for enhanced antimicrobial Property and biocompatibility
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Abstract
Emphasis on the importance of natural, alternative and eco-friendly
newlinecompounds is being made due to the rising health concerns of the chemicals
newlineinvolved in chemical based compounds and their detrimental consequences on
newlinethe environment. Hence, resorting to non toxic, natural and eco-friendly
newlinealternatives in reducing the utilization of chemical products and their induced
newlinechemical toxicity is paramount and gaining considerable attention.
newlineExisting therapeutic agents like nanomaterial based drugs or
newlinebiomaterials like biopolymers that have been used in medical applications
newlinethough possess benefits as biological agents, but have always required
newlineimprovements in their physical, chemical and biological properties enabling
newlinethem to be used more efficiently for several pharmacological or medical
newlineapplications. Nanoparticles though find immense applications in several
newlinemedical and environmental remediation processes, but their toxicity is a still
newlinemajor concern in utilizing them for biological applications. Phytochemicals
newlinecan thus prove to be very useful in reducing nanoparticle induced toxicity and
newlineimprove their biocompatibility.
newlineThe current research work focuses on the utilization of plant
newlineextracts and their constituent biomolecules (phytochemicals) as reducing
newlineagent in the synthesis of biocompatible iron oxide and CuO/ZnO
newlinenanoparticles and as functionalizing agent in the synthesis of chitosan films
newlinewith improved properties. The work involved three different phytochemical
newlinebased studies. Firstly, Borassus flabellifer seed coat extract has been used as a
newlinereducing agent in the synthesis of biocompatible magnetic iron oxide
newlinenanoparticles and involves the study of its various biological characteristics
newline