Effects of chlorpyrifos on some hematological and biochemical variables in rat a physiological study

Abstract

Chlorpyrifos (CPF) is a broad spectrum organophosphate insecticide which is widely used in agricultural and domestic sectors to fight against harmful insects (Sancherz et al., 2004).Right now, approximately 800 registered pesticide products in the market containchlorpyrifos(Dutta et al., 1992). Exposure to chlorpyrifos causes harmful effect on animal and humans (Zhao et al., 2005). Human beings are getting exposed to this chemical through ingestion of vegetables, inhalation and dermal exposure due to indiscriminate use of this chemicals (Caroline, 1991). After entering the body, it is absorbed quickly from the alimentary and respiratory tract, then metabolized and excreted through the urine and faeces (Davide et al., 2008).A few reports have stated that chlorpyrifos can alter the blood cholesterol and liver glycogen level. newline