Clinico Diagnostic Studies And Evaluation Of Certain Biomarkers In Canine Pyometra

Abstract

The aim of the present study was to identify the frequency of SIRS in newlinepyometra affected bitches and to study the role of certain biomarkers of diagnostic newlineand prognostic importance, along with evaluation of blood flow velocities and newlinehemodynamic indices in uterine artery and to study the hemato-biochemical, newlinehistopatholgical and immunohistochemical changes in canine pyometra. Out of 716 newlinebitches presented for various gynaecological ailments, 122 bitches were diagnosed newlinewith pyometra with an overall occurrence of 17.04 per cent. Bitches in the age group newlineof 6 to 9 years (29.51%) had high occurrence of pyometra followed by 3 to 6 years newline(28.69%), 9 to12 years (27.05%), 12 to 15 years (9.83%) and least in bitches upto 3 newlineyears of age (4.92%). The mean age of occurrence of pyometra was 8.03±0.26 years newlinewith a range of 2 to 15 years. The present study revealed high occurrence of pyometra newlinein Spitz (43.44%) followed by Labrador (22.95%), Mongrel (9.83%), German newlineShepard (7.38%), Pug (5.74%), Pomeranian (4.10%), Great Dane (2.46%), Doberman newline(1.64%), Dachshund, Bull Mastiff and Saint Bernard (0.82% each). Occurrence of newlinepyometra was highest in nulliparous (62.30%) bitches followed by primiparous newline(22.13%) and pluriparous (15.57%) bitches. The occurrence of open cervix (85.25%) newlinepyometra was higher than closed cervix (14.75%) pyometra. The most predominant newlinesymptom reported by the owners was presence of vaginal discharge (80.00%) newlinefollowed by inappetence (72.00%), polydipsia (74.60%), vomiting (68.00%), polyuria newline(57.30%) and diarrhoea (12.00%). The altered physiological findings on clinical newlineexamination were increased (28.00%) and decreased (1.33%) temperature, pale newline(28.00%) and hyperemic (6.67%) mucous membranes, mild (32.00%) to moderate newline(6.67%) dehydration, moderate (50.67%) to severe depression (34.67%) in pyometra newlineaffected bitches. On palpation of abdomen 24.00 per cent bitches expressed pain and newlineenlarged uterus was clearly felt in 32.00 per cent bitches and unclear in 68.00 per cent newlinebitches. The temperature and respiratory rate were