Formulation optimization characterization and pharmacokinetic study of chitosan modified PLGA nanoparticles for sustained delivery of Furosemide

Abstract

Advances in nanotechnology have provided access to new research avenues in the newlinefield of drug delivery. Nanoparticles, first developed around 1970s, are solid, newlinecolloidal particles consisting of macromolecular substances varying in size from 10 newlinenm to 1000 nm in which the active ingredients (drug or biologically active ingredient) newlineis dissolved, entrapped or encapsulated and/or to which the active ingredient is newlineadsorbed or attached to. newline