Synthetic investigations on Bisaryal Ureas, Bisphosphonates and Citalopram analogues as Pharmaceutically active Substances

Abstract

Nitrogen containing heterocyclic compounds are key building blocks used to develop compounds of biological or medicinal interest to chemists. A vast number of nitrogen containing heterocyclic building newlineblocks have applications in pharmaceutical research, agriculture science, and drug discovery. Most of the organic compounds containing nitrogen show better biological activity than non-nitrogen compounds. newlineKeeping in view of the importance of the nitrogen containing compounds, the present thesis describes the synthetic studies on some of the important category of drug substances particularly Sorafenib newlineanalogues, Citalopram analogues containing tetrazoles and Zoledronic acid, Ibandronicacid analogues. newline