Characterization and pharmacological activity of essential oil of some indigenous medicinal plants of Uttarakhand

dc.contributor.guideBachheti , R K and Bhushan, Brij
dc.coverage.spatialChemistry
dc.creator.researcherMahesh Chandra
dc.date.accessioned2016-02-16T04:35:50Z
dc.date.available2016-02-16T04:35:50Z
dc.date.awarded03/08/2015
dc.date.completed21/03/2015
dc.date.registered28-10-2010
dc.description.abstractNumerousaromaticandmedicinalplantsfromIndianHimalayaextensivelyusedasnaturalfoodadditivesorforhealthendorsementinIndiantraditionalmedicineInviewofthefactthatfromlongtimeessentialoilsareusedasflavoringagentsandconstituentsofnumerousimportantcommercialproductsDiverseChemicalprofilesoftheessentialoilareofgreatimportancetocharacterizationformultipleapplicationsInthepresentstudy,essentialoilsandhydro-alcoholicextractsobtainedfromplantsbelongingtoLamiaceae(Micromeriabiflora(Buch-HamexDDon)BenthandThymuslinearisBenth)andVerbenaceaefamily(CallicarpamacrophyllaVahl) newlineThehydro-distilledessentialoilswerecharacterizedfortheirphysico-chemicalpropertiesandmethanolicextractswereanalyzedforestimationofphenoliccontentsAlltheextractedessentialoilsandhydro-alcoholicextractswereevaluatedfortheirpharmacologicalactivitiesviz,antioxidant,anti-inflammatory,analgesic,antipyreticandantimicrobialactivitiesTheoilyieldsofselectedplantsvariedfrom0015%-087%TheessentialoilsfromtheselectedplantswereanalyzedbythecombinationofGasChromatographyandGasChromatography MassSpectrometoryAlltheessentialoilmostlyrevealedthechemicalconstituentsofoxygenatedmonoterpenesandsesquiterpeneswithmonoandsesquiterpeneshydrocarbons newlineTheessentialoilofMicromeriabiflora(Buch-HamexDDon)Benth(Lamiaceae)analyzedbyGCandGC/MSSixteencompoundscontributingto919%ofthetotaloilwereidentifiedTheoilwasdominatedbyoxygenatedsesquiterpenoidscaryophylleneoxide(425%),epi-and#945;-cadinol(57%),and#946;-eudesmol(93%),oplapanone(45%)andguaial(46%)and#945;-Terpeneol(11%)wastheonlyidentifiedoxygenatedmonoterpeneThemajormonoandsequiterpenehydrocarbonsidentifiedintheessentialoilwereþ-cymene(47%),and#947;-cadinene(26%),and#948;-cadinene(34%),andand#945;-cadinene(28%)besidesotherminorconstituentsTheessentialoilcompositionofThymuslineariscollectedfromtwodifferentlocations(Harinagar;Nainital(TLHEO)andandDhanatuallyNainital(TLEOD))TheGCandGC-MSanalysesoftheoilsofThymuslinearisfromboththecollectionwereinvestigatedTotalninemajorconstituentscontributingto936%wereidentifiedinTLHEOand893%inTLDEOsamplesGermacrene-D(651%)andand#947;-terpinene(194%)wereidentif
dc.description.note-
dc.format.accompanyingmaterialNone
dc.format.dimensions-
dc.format.extent-
dc.identifier.urihttp://hdl.handle.net/10603/72744
dc.languageEnglish
dc.publisher.institutionDepartment of Chemistry
dc.publisher.placeDehradun
dc.publisher.universityGraphic Era University
dc.relation-
dc.rightsuniversity
dc.source.universityUniversity
dc.subject.keywordChemistry
dc.titleCharacterization and pharmacological activity of essential oil of some indigenous medicinal plants of Uttarakhand
dc.title.alternative-
dc.type.degreePh.D.

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